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talquetamab will increase the amount or effect of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Talquetamab leads to cytokine launch syndrome (CRS) that could suppress exercise of CYP enzymes, leading to improved publicity of CYP substrates.Simply because CYP3A4 inhibition elevates ergotamine and ca